What is Peptide PNC-27?
Peptide PNC-27 is a synthetic peptide designed to target and eliminate cancer cells. It was initially developed as a potential treatment for various types of cancer, including pancreatic cancer and leukaemia. The peptide is known for its ability to bind to the HDM-2 protein, which is overexpressed in cancer cells, leading to cell necrosis.
What is Peptide PNC-27 Used For?
The primary application of Peptide PNC-27 is in cancer research. It has shown promising results in preclinical studies for its anti-cancer activity. Researchers are particularly interested in its potential to treat acute myeloid leukaemia (AML) and other forms of cancer.
How Does Peptide PNC-27 Work?
Peptide PNC-27 works by binding to the HDM-2 protein found in the membranes of cancer cells. This binding action triggers cell necrosis, effectively eliminating the cancerous cells. The peptide does not appear to harm healthy cells, making it a subject of interest for targeted cancer therapies.
Research Studies on Peptide PNC-27
- A study published on PubMed describes how PNC-27 binds to the HDM-2 protein expressed in cancer cell membranes and induces tumour cell necrosis.
- Another article from the American Society of Hematology discusses its potential efficacy against acute myeloid leukaemia (AML).
How is Peptide PNC-27 Stored?
Peptide PNC-27 should be stored in a cool, dry place, preferably at -20°C for long-term storage. It is recommended to use bacteriostatic water for reconstitution.
Note on Research Dosages
Specific information on research dosages for Peptide PNC-27 is currently limited. Researchers are advised to consult primary literature and follow institutional guidelines for experimental protocols.