What is AICAR
AICAR uses metabolic pathways to block certain enzymes, allowing AMP-activated protein kinase. This can be explained to the layperson like this: once you take a substantial amount of AICAR, it tricks your body at a cellular level into thinking that exercise has just been performed. Since the body thinks it has just done a considerable amount of exercise, the energy cycle at the cellular level starts converting fuel sources, like fatty acids, to output the energy that was thought to have been spent during exercise. This can have a direct effect on the level of endurance activity and the sustainability of that activity. Insulin sensitivity is also noted as one action that AICAR produces, as the body will think it just went through a series of exercises.
Interestingly, in animal studies with obese mice, AICAR showed all of the peptide benefits for obese diet-induced mice, yet the healthy lean mice did not reap any of the benefits of insulin sensitivity or an increase in glucose uptake. That being said, the application in bodybuilding does not seem very suitable, as these mechanisms are targeted at the out-of-shape and overweight, so if you are not a top-level endurance athlete.
Dosage Suggestion
Mix 1 ml water with each Vial of AICAR. one full insulin syringe of water.
Only mix one bottle of each at a time and keep refrigerated.
The most popular dosage is 20ml
Dosage :
40iu of AICAR first thing in the morning, = 20mg
50iu of AICAR first thing in the morning, = 25mg
Your last meal should be a protein source like chicken, fish, lean steak and vegetables. A very small portion of carbs only. Even better if you can do without the carbs on your last meal.
