Remember way back when I addressed the amazing ability GHRP-6 has in improving the production of the hormone ghrelin in the stomach (a hormone that controls hunger and GH release)? Well let me tell you about GHRP-2 and why this peptide is one step better than its little brother GHRP-6. Unlike GHRP-6 , GHRP-2 does not come with the heavy hunger side effect, but still maintains all the benefits of activating ghrelin. You may be contemplating why is ghrelin so important for a growth hormone releasing peptide? Let’s take a closer look.
How does it Work?
The single polypeptide chain composed of six amino acids is a growth hormone releasing peptide. This hexapeptide not only functions to stimulate ghrelin release, but it also works to correct production of low level growth hormone. Simply put, GHRP-2 is perfectly designed with the intention of releasing human growth hormone from the pituitary gland. These mechanisms have been shown to promote lean body gains in lean body individuals. Since GHRP-2 is a ghrelin agonist, it helps to promote the secretion of human growth hormone in a two fold process. For one, it acts to boost growth hormone through amplification of the transduction pathway. In addition, it suppresses the action of somatostatin (a hormone which limits the release of growth hormone). These actions make GHRP-2 a perfect option to increase endogenous growth hormone levels.
As I have already stated, the hunger side effects tied to GHRP-2 should be duly noted. Usage of this peptide can also come with elevated levels of cortisol and prolactin, especially if users are dosing in the higher ranges – over 200mcg/injection. Another common side effect is the feeling of lethargy and tiredness upon first using GHRP-2. Water retention, tingling, numbness and decreased insulin sensitivity have also been cataloged as effects of GHRP-2. The most common positive side effect that bodybuilders and athletes will find with GHRP-2 are: decreased body fat, increase lean body mass, improved sleep, increase in IGF-1 production, increase in bone density and increase in cellular repair. While GHRP-2 has good and bad side effects, it should also be taken into consideration that compared to Hexarelin or GHRP-6, GHRP-2 is actually the mildest GHRP next in line to Ipamorelin.