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Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging

Highlights •A modified FOXO4-p53 interfering peptide causes p53 nuclear exclusion in senescent cells •This FOXO4 peptide induces targeted apoptosis of senescent cells (TASC) •TASC neutralizes murine liver chemotoxicity from doxorubicin Continue reading